丹(dan)麥Nordic Bioscience宣布，其CPa9-HNE生物標(biao)志物檢測(ce)獲(huo)得FDA支持信。CPa9-HNE可識別(bie)血液中(zhong)(zhong)(zhong)中(zhong)(zhong)(zhong)性(xing)(xing)粒細胞(bao)的(de)活化(hua)狀態，用于(yu)測(ce)量由人類(lei)中(zhong)(zhong)(zhong)性(xing)(xing)粒細胞(bao)彈性(xing)(xing)蛋(dan)白酶產(chan)生的(de)鈣衛蛋(dan)白S100a9片段。在炎癥性(xing)(xing)腸病(bing)(bing)(IBD)患(huan)者的(de)血清和(he)血漿中(zhong)(zhong)(zhong)檢測(ce)到，并定量活化(hua)的(de)中(zhong)(zhong)(zhong)性(xing)(xing)粒細胞(bao)，提供疾(ji)病(bing)(bing)活動非侵(qin)入性(xing)(xing)指(zhi)標(biao)。該(gai)標(biao)志物有望用于(yu)未來臨床(chuang)試驗中(zhong)(zhong)(zhong)的(de)患(huan)者篩選(xuan)工具，幫助(zhu)識別(bie)更可能出現內(nei)窺鏡下疾(ji)病(bing)(bing)活動的(de)患(huan)者。(美通社)